K261-1170 Screening compound: 2-(4-acetylphenyl)-4-[2-(4-methylphenyl)-2-oxoethyl]-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione

K261-1170 Screening compound: 2-(4-acetylphenyl)-4-[2-(4-methylphenyl)-2-oxoethyl]-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione
K261-1170 Screening compound: 2-(4-acetylphenyl)-4-[2-(4-methylphenyl)-2-oxoethyl]-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione alternative view

Chemical Structure Depiction of ChemDiv screening compound K261-1170
2-(4-acetylphenyl)-4-[2-(4-methylphenyl)-2-oxoethyl]-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K261-1170

Molecular Formula

C24H20N2O5S (C24 H20 N2 O5 S)

Compound Name

2-(4-acetylphenyl)-4-[2-(4-methylphenyl)-2-oxoethyl]-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione

IUPAC name

2-(4-acetylphenyl)-4-[2-(4-methylphenyl)-2-oxoethyl]-34-dihydro-2H-1lambda624-benzothiadiazine-113-trione

SMILES

CC(c(cc1)ccc1N(C(N(CC(c1ccc(C)cc1)=O)c1c2cccc1)=O)S2(=O)=O)=O

InChI

InChI=1S/C24H20N2O5S/c1-16-7-9-19(10-8-16)22(28)15-25-21-5-3-4-6-23(21)32(30,31)26(24(25)29)20-13-11-18(12-14-20)17(2)27/h3-14H,15H2,1-2H3

InChI Key

GHOKQPSXVZWPNP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15084366

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.5

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.570

Distribution Coefficient, logD

3.570

Water Solubility, LogSw

-3.87

Polar Surface Area

73.816

Acid Dissociation Constant (pKa)

20.76

Base Dissociation Constant (pKb)

-12.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

K261-1170 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K261-1170 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K261-1170?
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What is the minimum amount of K261-1170 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K261-1170
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K261-1170
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K261-1170 available by request