K263-0422 Screening compound: 2-{[3-(3-morpholinopropyl)-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

K263-0422 Screening compound: 2-{[3-(3-morpholinopropyl)-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
K263-0422 Screening compound: 2-{[3-(3-morpholinopropyl)-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K263-0422
2-{[3-(3-morpholinopropyl)-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K263-0422

Molecular Formula

C19H22N4O3S2 (C19 H22 N4 O3 S2)

Compound Name

2-{[3-(3-morpholinopropyl)-4-oxo-3,4-dihydro[1]benzothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide

IUPAC name

2-({5-[3-(morpholin-4-yl)propyl]-6-oxo-8-thia-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)31012-pentaen-4-yl}sulfanyl)acetamide

SMILES

NC(CSC(N(CCCN1CCOCC1)C1=O)=Nc2c1sc1c2cccc1)=O

InChI

InChI=1S/C19H22N4O3S2/c20-15(24)12-27-19-21-16-13-4-1-2-5-14(13)28-17(16)18(25)23(19)7-3-6-22-8-10-26-11-9-22/h1-2,4-5H,3,6-12H2,(H2,20,24)

InChI Key

PRSAXNYTKSUHPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15085465

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.554

Distribution Coefficient, logD

1.471

Water Solubility, LogSw

-2.16

Polar Surface Area

69.795

Acid Dissociation Constant (pKa)

15.86

Base Dissociation Constant (pKb)

6.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

K263-0422 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Ion Channels Focused Library (26372 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with K263-0422 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K263-0422?
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What is the minimum amount of K263-0422 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K263-0422
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K263-0422
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K263-0422 available by request