K264-0165 Screening compound: 4-amino-5-benzoyl-2-[(2-ethoxyphenyl)amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)thiophene-3-carboxamide

K264-0165 Screening compound: 4-amino-5-benzoyl-2-[(2-ethoxyphenyl)amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)thiophene-3-carboxamide
K264-0165 Screening compound: 4-amino-5-benzoyl-2-[(2-ethoxyphenyl)amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)thiophene-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K264-0165
4-amino-5-benzoyl-2-[(2-ethoxyphenyl)amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)thiophene-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K264-0165

Molecular Formula

C30H29N3O3S (C30 H29 N3 O3 S)

Compound Name

4-amino-5-benzoyl-2-[(2-ethoxyphenyl)amino]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)thiophene-3-carboxamide

IUPAC name

4-amino-5-benzoyl-2-[(2-ethoxyphenyl)amino]-N-(1234-tetrahydronaphthalen-1-yl)thiophene-3-carboxamide

SMILES

CCOc(cccc1)c1Nc1c(C(NC(CCC2)c3c2cccc3)=O)c(N)c(C(c2ccccc2)=O)s1

InChI

InChI=1S/C30H29N3O3S/c1-2-36-24-18-9-8-16-23(24)33-30-25(26(31)28(37-30)27(34)20-12-4-3-5-13-20)29(35)32-22-17-10-14-19-11-6-7-15-21(19)22/h3-9,11-13,15-16,18,22,33H,2,10,14,17,31H2,1H3,(H,32,35)/t22-/m0/s1

InChI Key

MILUJGLYHSIULN-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD15085728

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

511.64

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.352

Distribution Coefficient, logD

6.352

Water Solubility, LogSw

-5.63

Polar Surface Area

72.568

Acid Dissociation Constant (pKa)

12.99

Base Dissociation Constant (pKb)

-2.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

K264-0165 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • Epigenetic

References: we are preparing a list of scientific research reports with K264-0165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K264-0165?
Check Price and Availability of K264-0165, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K264-0165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K264-0165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K264-0165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K264-0165 available by request