K264-0445 Screening compound: 5-benzoyl-3-(4-bromobenzenesulfonyl)-N2-[4-(propan-2-yl)phenyl]thiophene-2,4-diamine

K264-0445 Screening compound: 5-benzoyl-3-(4-bromobenzenesulfonyl)-N2-[4-(propan-2-yl)phenyl]thiophene-2,4-diamine
K264-0445 Screening compound: 5-benzoyl-3-(4-bromobenzenesulfonyl)-N2-[4-(propan-2-yl)phenyl]thiophene-2,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound K264-0445
5-benzoyl-3-(4-bromobenzenesulfonyl)-N2-[4-(propan-2-yl)phenyl]thiophene-2,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K264-0445

Molecular Formula

C26H23BrN2O3S2 (C26 H23 BrN2 O3 S2)

Compound Name

5-benzoyl-3-(4-bromobenzenesulfonyl)-N2-[4-(propan-2-yl)phenyl]thiophene-2,4-diamine

IUPAC name

5-benzoyl-3-(4-bromobenzenesulfonyl)-N2-[4-(propan-2-yl)phenyl]thiophene-24-diamine

SMILES

CC(C)c(cc1)ccc1Nc(sc(C(c1ccccc1)=O)c1N)c1S(c(cc1)ccc1Br)(=O)=O

InChI

InChI=1S/C26H23BrN2O3S2/c1-16(2)17-8-12-20(13-9-17)29-26-25(34(31,32)21-14-10-19(27)11-15-21)22(28)24(33-26)23(30)18-6-4-3-5-7-18/h3-16,29H,28H2,1-2H3

InChI Key

CJZMNXGHWVIKJT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15085787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

555.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.177

Distribution Coefficient, logD

7.177

Water Solubility, LogSw

-5.87

Polar Surface Area

71.299

Acid Dissociation Constant (pKa)

18.44

Base Dissociation Constant (pKb)

-5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

K264-0445 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K264-0445 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K264-0445?
Check Price and Availability of K264-0445, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K264-0445 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K264-0445
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K264-0445
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K264-0445 available by request