K264-0455 Screening compound: 5-(4-bromobenzoyl)-3-(3-chloro-4-fluorobenzenesulfonyl)-N2-(2,6-dimethylphenyl)thiophene-2,4-diamine

K264-0455 Screening compound: 5-(4-bromobenzoyl)-3-(3-chloro-4-fluorobenzenesulfonyl)-N2-(2,6-dimethylphenyl)thiophene-2,4-diamine
K264-0455 Screening compound: 5-(4-bromobenzoyl)-3-(3-chloro-4-fluorobenzenesulfonyl)-N2-(2,6-dimethylphenyl)thiophene-2,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound K264-0455
5-(4-bromobenzoyl)-3-(3-chloro-4-fluorobenzenesulfonyl)-N2-(2,6-dimethylphenyl)thiophene-2,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K264-0455

Molecular Formula

C25H19BrClFN2O3S2 (C25 H19 BrClFN2 O3 S2)

Compound Name

5-(4-bromobenzoyl)-3-(3-chloro-4-fluorobenzenesulfonyl)-N2-(2,6-dimethylphenyl)thiophene-2,4-diamine

IUPAC name

5-(4-bromobenzoyl)-3-(3-chloro-4-fluorobenzenesulfonyl)-N2-(26-dimethylphenyl)thiophene-24-diamine

SMILES

Cc1cccc(C)c1Nc(sc(C(c(cc1)ccc1Br)=O)c1N)c1S(c(cc1)cc(Cl)c1F)(=O)=O

InChI

InChI=1S/C25H19BrClFN2O3S2/c1-13-4-3-5-14(2)21(13)30-25-24(35(32,33)17-10-11-19(28)18(27)12-17)20(29)23(34-25)22(31)15-6-8-16(26)9-7-15/h3-12,30H,29H2,1-2H3

InChI Key

XHYJGASIPKSKLZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15085797

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

593.92

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.566

Distribution Coefficient, logD

6.566

Water Solubility, LogSw

-6.32

Polar Surface Area

69.904

Acid Dissociation Constant (pKa)

18.08

Base Dissociation Constant (pKb)

-5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

K264-0455 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Others
  • GPCR
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K264-0455 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K264-0455?
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What is the minimum amount of K264-0455 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K264-0455
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K264-0455
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K264-0455 available by request