K271-0014 Screening compound: N-benzyl-2-hydroxy-2-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetamide

K271-0014 Screening compound: N-benzyl-2-hydroxy-2-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetamide
K271-0014 Screening compound: N-benzyl-2-hydroxy-2-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K271-0014
N-benzyl-2-hydroxy-2-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K271-0014

Molecular Formula

C17H14N2O3 (C17 H14 N2 O3)

Compound Name

N-benzyl-2-hydroxy-2-[(3E)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]acetamide

IUPAC name

N-benzyl-2-hydroxy-2-[(3E)-2-oxo-23-dihydro-1H-indol-3-ylidene]acetamide

SMILES

O/C(/C(NCc1ccccc1)=O)=C(\c(cccc1)c1N1)/C1=O

InChI

InChI=1S/C17H14N2O3/c20-15(17(22)18-10-11-6-2-1-3-7-11)14-12-8-4-5-9-13(12)19-16(14)21/h1-9,20H,10H2,(H,18,22)(H,19,21)

InChI Key

YNJGFHBEZLCMJN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15085811

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

294.31

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.674

Distribution Coefficient, logD

1.622

Water Solubility, LogSw

-2.52

Polar Surface Area

66.446

Acid Dissociation Constant (pKa)

8.29

Base Dissociation Constant (pKb)

0.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

K271-0014 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K271-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K271-0014?
Check Price and Availability of K271-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K271-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K271-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K271-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K271-0014 available by request