K273-0169 Screening compound: 16-[(Z,2E)-3-(4-chlorophenyl)-1-hydroxy-2-propenylidene]-14-methyl-2-oxa-14-azatetracyclo[7.4.3.0~1,10~.0~3,8~]hexadeca-3,5,7-trien-15-one

K273-0169 Screening compound: 16-[(Z,2E)-3-(4-chlorophenyl)-1-hydroxy-2-propenylidene]-14-methyl-2-oxa-14-azatetracyclo[7.4.3.0~1,10~.0~3,8~]hexadeca-3,5,7-trien-15-one
K273-0169 Screening compound: 16-[(Z,2E)-3-(4-chlorophenyl)-1-hydroxy-2-propenylidene]-14-methyl-2-oxa-14-azatetracyclo[7.4.3.0~1,10~.0~3,8~]hexadeca-3,5,7-trien-15-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K273-0169
16-[(Z,2E)-3-(4-chlorophenyl)-1-hydroxy-2-propenylidene]-14-methyl-2-oxa-14-azatetracyclo[7.4.3.0~1,10~.0~3,8~]hexadeca-3,5,7-trien-15-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K273-0169

Molecular Formula

C24H22ClNO3 (C24 H22 ClNO3)

Compound Name

16-[(Z,2E)-3-(4-chlorophenyl)-1-hydroxy-2-propenylidene]-14-methyl-2-oxa-14-azatetracyclo[7.4.3.0~1,10~.0~3,8~]hexadeca-3,5,7-trien-15-one

IUPAC name

(16Z)-16-[(2E)-3-(4-chlorophenyl)-1-hydroxyprop-2-en-1-ylidene]-14-methyl-2-oxa-14-azatetracyclo[7.4.3.0^{110}.0^{38}]hexadeca-357-trien-15-one

SMILES

CN(C(CCC1)(C1C1/C2=C(\C=C\c(cc3)ccc3Cl)/O)Oc3c1cccc3)C2=O

InChI

InChI=1S/C24H22ClNO3/c1-26-23(28)22(19(27)13-10-15-8-11-16(25)12-9-15)21-17-5-2-3-7-20(17)29-24(26)14-4-6-18(21)24/h2-3,5,7-13,18,21,27H,4,6,14H2,1H3

InChI Key

GPAVDNTZJUBJBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05030022

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.814

Distribution Coefficient, logD

4.814

Water Solubility, LogSw

-5.00

Polar Surface Area

39.155

Acid Dissociation Constant (pKa)

11.80

Base Dissociation Constant (pKb)

-0.72

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

29.20

K273-0169 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

DGK Inhibitors Library (10558 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with K273-0169 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K273-0169?
Check Price and Availability of K273-0169, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K273-0169 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K273-0169
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K273-0169
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K273-0169 available by request