K273-0603 Screening compound: 4-chloro-12-(2-methoxybenzoyl)-9-methyl-8-oxa-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-11-one

K273-0603 Screening compound: 4-chloro-12-(2-methoxybenzoyl)-9-methyl-8-oxa-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-11-one
K273-0603 Screening compound: 4-chloro-12-(2-methoxybenzoyl)-9-methyl-8-oxa-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-11-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K273-0603
4-chloro-12-(2-methoxybenzoyl)-9-methyl-8-oxa-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-11-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K273-0603

Molecular Formula

C20H18ClNO4 (C20 H18 ClNO4)

Compound Name

4-chloro-12-(2-methoxybenzoyl)-9-methyl-8-oxa-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-11-one

IUPAC name

n/a

SMILES

CC(CC1C2C(c(cccc3)c3OC)=O)(NC2=O)Oc(cc2)c1cc2Cl

InChI

InChI=1S/C20H18ClNO4/c1-20-10-14(13-9-11(21)7-8-16(13)26-20)17(19(24)22-20)18(23)12-5-3-4-6-15(12)25-2/h3-9,14,17H,10H2,1-2H3,(H,22,24)

InChI Key

VEUYTYUFIYBKAF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15086386

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.82

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.434

Distribution Coefficient, logD

3.432

Water Solubility, LogSw

-3.86

Polar Surface Area

53.623

Acid Dissociation Constant (pKa)

9.88

Base Dissociation Constant (pKb)

-4.51

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

30.00

K273-0603 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

DGK Inhibitors Library (10558 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K273-0603 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K273-0603?
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What is the minimum amount of K273-0603 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K273-0603
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K273-0603
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K273-0603 available by request