K277-0128 Screening compound: 3-[4-(3,4-dichlorophenyl)-5-methyl-1,3-thiazol-2-yl]-2H-chromen-2-one

K277-0128 Screening compound: 3-[4-(3,4-dichlorophenyl)-5-methyl-1,3-thiazol-2-yl]-2H-chromen-2-one
K277-0128 Screening compound: 3-[4-(3,4-dichlorophenyl)-5-methyl-1,3-thiazol-2-yl]-2H-chromen-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K277-0128
3-[4-(3,4-dichlorophenyl)-5-methyl-1,3-thiazol-2-yl]-2H-chromen-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K277-0128

Molecular Formula

C19H11Cl2NO2S (C19 H11 Cl2 NO2 S)

Compound Name

3-[4-(3,4-dichlorophenyl)-5-methyl-1,3-thiazol-2-yl]-2H-chromen-2-one

IUPAC name

3-[4-(34-dichlorophenyl)-5-methyl-13-thiazol-2-yl]-2H-chromen-2-one

SMILES

Cc1c(-c(cc2)cc(Cl)c2Cl)nc(C2=Cc(cccc3)c3OC2=O)s1

InChI

InChI=1S/C19H11Cl2NO2S/c1-10-17(12-6-7-14(20)15(21)9-12)22-18(25-10)13-8-11-4-2-3-5-16(11)24-19(13)23/h2-9H,1H3

InChI Key

NGMWMSIWOPJNPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02733256

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.27

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.142

Distribution Coefficient, logD

6.142

Water Solubility, LogSw

-6.22

Polar Surface Area

31.393

Acid Dissociation Constant (pKa)

27.17

Base Dissociation Constant (pKb)

-4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

K277-0128 in Drug Discovery

Included in Screening Libraries

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K277-0128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K277-0128?
Check Price and Availability of K277-0128, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K277-0128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K277-0128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K277-0128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K277-0128 available by request