K280-0483 Screening compound: N-(2-fluorophenyl)-2-({2-[2-(2-methyl-1H-1,3-benzodiazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)butanamide

K280-0483 Screening compound: N-(2-fluorophenyl)-2-({2-[2-(2-methyl-1H-1,3-benzodiazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)butanamide
K280-0483 Screening compound: N-(2-fluorophenyl)-2-({2-[2-(2-methyl-1H-1,3-benzodiazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K280-0483
N-(2-fluorophenyl)-2-({2-[2-(2-methyl-1H-1,3-benzodiazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K280-0483

Molecular Formula

C29H26FN7OS (C29 H26 FN7 OS)

Compound Name

N-(2-fluorophenyl)-2-({2-[2-(2-methyl-1H-1,3-benzodiazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)butanamide

IUPAC name

N-(2-fluorophenyl)-2-({2-[2-(2-methyl-1H-13-benzodiazol-1-yl)ethyl]-[124]triazolo[15-c]quinazolin-5-yl}sulfanyl)butanamide

SMILES

CCC(C(Nc(cccc1)c1F)=O)Sc1nc(cccc2)c2c2nc(CCn3c(cccc4)c4nc3C)nn12

InChI

InChI=1S/C29H26FN7OS/c1-3-25(28(38)32-22-13-7-5-11-20(22)30)39-29-33-21-12-6-4-10-19(21)27-34-26(35-37(27)29)16-17-36-18(2)31-23-14-8-9-15-24(23)36/h4-15,25H,3,16-17H2,1-2H3,(H,32,38)/t25-/m0/s1

InChI Key

QHKBJXDYYVCUNF-VWLOTQADSA-N

MDL Number (MFCD)

MFCD15087491

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

539.64

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.854

Distribution Coefficient, logD

5.738

Water Solubility, LogSw

-5.69

Polar Surface Area

64.408

Acid Dissociation Constant (pKa)

10.49

Base Dissociation Constant (pKb)

6.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.70

K280-0483 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with K280-0483 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K280-0483?
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What is the minimum amount of K280-0483 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K280-0483
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K280-0483
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K280-0483 available by request