K280-0486 Screening compound: 7-chloro-2-[({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one

K280-0486 Screening compound: 7-chloro-2-[({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one
K280-0486 Screening compound: 7-chloro-2-[({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K280-0486
7-chloro-2-[({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K280-0486

Molecular Formula

C24H19ClN8OS (C24 H19 ClN8 OS)

Compound Name

7-chloro-2-[({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one

IUPAC name

7-chloro-2-[({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[124]triazolo[15-c]quinazolin-5-yl}sulfanyl)methyl]-4H-pyrido[12-a]pyrimidin-4-one

SMILES

Cc1cncn1CCc1nn2c(SCC(N=C(C=C3)N4C=C3Cl)=CC4=O)nc(cccc3)c3c2n1

InChI

InChI=1S/C24H19ClN8OS/c1-15-11-26-14-31(15)9-8-20-29-23-18-4-2-3-5-19(18)28-24(33(23)30-20)35-13-17-10-22(34)32-12-16(25)6-7-21(32)27-17/h2-7,10-12,14H,8-9,13H2,1H3

InChI Key

SSUFGKCTYLUAGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15087494

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

502.99

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.594

Distribution Coefficient, logD

1.077

Water Solubility, LogSw

-3.12

Polar Surface Area

68.932

Acid Dissociation Constant (pKa)

22.63

Base Dissociation Constant (pKb)

8.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

K280-0486 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K280-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K280-0486?
Check Price and Availability of K280-0486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K280-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K280-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K280-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K280-0486 available by request