K280-0493 Screening compound: 2-({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide

K280-0493 Screening compound: 2-({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide
K280-0493 Screening compound: 2-({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K280-0493
2-({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K280-0493

Molecular Formula

C24H20F3N7OS (C24 H20 F3 N7 OS)

Compound Name

2-({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-({2-[2-(5-methyl-1H-imidazol-1-yl)ethyl]-[124]triazolo[15-c]quinazolin-5-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide

SMILES

Cc1cncn1CCc1nn2c(SCC(Nc3c(C(F)(F)F)cccc3)=O)nc(cccc3)c3c2n1

InChI

InChI=1S/C24H20F3N7OS/c1-15-12-28-14-33(15)11-10-20-31-22-16-6-2-4-8-18(16)30-23(34(22)32-20)36-13-21(35)29-19-9-5-3-7-17(19)24(25,26)27/h2-9,12,14H,10-11,13H2,1H3,(H,29,35)

InChI Key

QSDUVYIIIGGBPL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15087496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

511.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.818

Distribution Coefficient, logD

2.301

Water Solubility, LogSw

-3.70

Polar Surface Area

64.878

Acid Dissociation Constant (pKa)

12.59

Base Dissociation Constant (pKb)

8.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

K280-0493 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

CORONAVIRUS Library (20774 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with K280-0493 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K280-0493?
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What is the minimum amount of K280-0493 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K280-0493
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K280-0493
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K280-0493 available by request