K280-0566 Screening compound: 2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(3-methoxyphenyl)butanamide

K280-0566 Screening compound: 2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(3-methoxyphenyl)butanamide
K280-0566 Screening compound: 2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(3-methoxyphenyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K280-0566
2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(3-methoxyphenyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K280-0566

Molecular Formula

C27H29N7O2S (C27 H29 N7 O2 S)

Compound Name

2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(3-methoxyphenyl)butanamide

IUPAC name

2-({2-[2-(35-dimethyl-1H-pyrazol-4-yl)ethyl]-[124]triazolo[15-c]quinazolin-5-yl}sulfanyl)-N-(3-methoxyphenyl)butanamide

SMILES

CCC(C(Nc1cc(OC)ccc1)=O)Sc1nc(cccc2)c2c2nc(CCc3c(C)[nH]nc3C)nn12

InChI

InChI=1S/C27H29N7O2S/c1-5-23(26(35)28-18-9-8-10-19(15-18)36-4)37-27-29-22-12-7-6-11-21(22)25-30-24(33-34(25)27)14-13-20-16(2)31-32-17(20)3/h6-12,15,23H,5,13-14H2,1-4H3,(H,28,35)(H,31,32)/t23-/m0/s1

InChI Key

NRFQAEPSZSHXEM-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD15087554

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

515.64

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.274

Distribution Coefficient, logD

4.575

Water Solubility, LogSw

-5.43

Polar Surface Area

85.609

Acid Dissociation Constant (pKa)

11.40

Base Dissociation Constant (pKb)

8.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.60

K280-0566 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K280-0566 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K280-0566?
Check Price and Availability of K280-0566, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K280-0566 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K280-0566
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K280-0566
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K280-0566 available by request