K280-0583 Screening compound: 2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(2-fluorophenyl)butanamide

K280-0583 Screening compound: 2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(2-fluorophenyl)butanamide
K280-0583 Screening compound: 2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(2-fluorophenyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K280-0583
2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(2-fluorophenyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K280-0583

Molecular Formula

C26H26FN7OS (C26 H26 FN7 OS)

Compound Name

2-({2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-c]quinazolin-5-yl}sulfanyl)-N-(2-fluorophenyl)butanamide

IUPAC name

2-({2-[2-(35-dimethyl-1H-pyrazol-4-yl)ethyl]-[124]triazolo[15-c]quinazolin-5-yl}sulfanyl)-N-(2-fluorophenyl)butanamide

SMILES

CCC(C(Nc(cccc1)c1F)=O)Sc1nc(cccc2)c2c2nc(CCc3c(C)[nH]nc3C)nn12

InChI

InChI=1S/C26H26FN7OS/c1-4-22(25(35)28-21-12-8-6-10-19(21)27)36-26-29-20-11-7-5-9-18(20)24-30-23(33-34(24)26)14-13-17-15(2)31-32-16(17)3/h5-12,22H,4,13-14H2,1-3H3,(H,28,35)(H,31,32)/t22-/m0/s1

InChI Key

PKFAHYQXSYFOBD-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD15087570

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

503.6

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.287

Distribution Coefficient, logD

4.587

Water Solubility, LogSw

-5.47

Polar Surface Area

77.368

Acid Dissociation Constant (pKa)

10.49

Base Dissociation Constant (pKb)

8.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.90

K280-0583 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K280-0583 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K280-0583?
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What is the minimum amount of K280-0583 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K280-0583
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K280-0583
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K280-0583 available by request