K284-1166 Screening compound: N~3~-(2,3-dimethylcyclohexyl)-6-thioxo-5,6-dihydro[1,3]benzimidazo[1,2-c]quinazoline-3-carboxamide

K284-1166 Screening compound: N~3~-(2,3-dimethylcyclohexyl)-6-thioxo-5,6-dihydro[1,3]benzimidazo[1,2-c]quinazoline-3-carboxamide
K284-1166 Screening compound: N~3~-(2,3-dimethylcyclohexyl)-6-thioxo-5,6-dihydro[1,3]benzimidazo[1,2-c]quinazoline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1166
N~3~-(2,3-dimethylcyclohexyl)-6-thioxo-5,6-dihydro[1,3]benzimidazo[1,2-c]quinazoline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1166

Molecular Formula

C23H24N4OS (C23 H24 N4 OS)

Compound Name

N~3~-(2,3-dimethylcyclohexyl)-6-thioxo-5,6-dihydro[1,3]benzimidazo[1,2-c]quinazoline-3-carboxamide

IUPAC name

N-(23-dimethylcyclohexyl)-9-sulfanylidene-81017-triazatetracyclo[8.7.0.0^{27}.0^{1116}]heptadeca-1(17)24611(16)1214-heptaene-5-carboxamide

SMILES

CC(CCC1)C(C)C1NC(c(cc1)cc(N2)c1-c1nc(cccc3)c3n1C2=S)=O

InChI

InChI=1S/C23H24N4OS/c1-13-6-5-8-17(14(13)2)25-22(28)15-10-11-16-19(12-15)26-23(29)27-20-9-4-3-7-18(20)24-21(16)27/h3-4,7,9-14,17H,5-6,8H2,1-2H3,(H,25,28)(H,26,29)

InChI Key

QRUHLLDNFCFIAA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02935162

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.411

Distribution Coefficient, logD

4.328

Water Solubility, LogSw

-4.29

Polar Surface Area

46.932

Acid Dissociation Constant (pKa)

11.42

Base Dissociation Constant (pKb)

6.72

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

34.80

K284-1166 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-1166 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1166?
Check Price and Availability of K284-1166, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-1166 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1166
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1166
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1166 available by request