K284-1259 Screening compound: 6-(2-{[(benzylcarbamoyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)-N-[(furan-2-yl)methyl]hexanamide

K284-1259 Screening compound: 6-(2-{[(benzylcarbamoyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)-N-[(furan-2-yl)methyl]hexanamide
K284-1259 Screening compound: 6-(2-{[(benzylcarbamoyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)-N-[(furan-2-yl)methyl]hexanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1259
6-(2-{[(benzylcarbamoyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)-N-[(furan-2-yl)methyl]hexanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1259

Molecular Formula

C28H30N4O4S (C28 H30 N4 O4 S)

Compound Name

6-(2-{[(benzylcarbamoyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)-N-[(furan-2-yl)methyl]hexanamide

IUPAC name

6-(2-{[(benzylcarbamoyl)methyl]sulfanyl}-4-oxo-34-dihydroquinazolin-3-yl)-N-[(furan-2-yl)methyl]hexanamide

SMILES

O=C(CCCCCN1C(SCC(NCc2ccccc2)=O)=Nc(cccc2)c2C1=O)NCc1ccco1

InChI

InChI=1S/C28H30N4O4S/c33-25(30-19-22-12-9-17-36-22)15-5-2-8-16-32-27(35)23-13-6-7-14-24(23)31-28(32)37-20-26(34)29-18-21-10-3-1-4-11-21/h1,3-4,6-7,9-14,17H,2,5,8,15-16,18-20H2,(H,29,34)(H,30,33)

InChI Key

WHRNYFGCNUHCHV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05024051

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

518.64

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

15.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.497

Distribution Coefficient, logD

3.497

Water Solubility, LogSw

-3.80

Polar Surface Area

82.441

Acid Dissociation Constant (pKa)

12.83

Base Dissociation Constant (pKb)

1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

K284-1259 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

CORONAVIRUS Library (20774 compounds)

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with K284-1259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1259?
Check Price and Availability of K284-1259, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-1259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1259 available by request