K284-1365 Screening compound: ethyl 3-oxo-4-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)butanoate

K284-1365 Screening compound: ethyl 3-oxo-4-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)butanoate
K284-1365 Screening compound: ethyl 3-oxo-4-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)butanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1365
ethyl 3-oxo-4-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)butanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1365

Molecular Formula

C22H23N3O6S2 (C22 H23 N3 O6 S2)

Compound Name

ethyl 3-oxo-4-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-3,4-dihydroquinazolin-2-yl}sulfanyl)butanoate

IUPAC name

ethyl 3-oxo-4-({4-oxo-3-[2-(4-sulfamoylphenyl)ethyl]-34-dihydroquinazolin-2-yl}sulfanyl)butanoate

SMILES

CCOC(CC(CSC(N1CCc(cc2)ccc2S(N)(=O)=O)=Nc(cccc2)c2C1=O)=O)=O

InChI

InChI=1S/C22H23N3O6S2/c1-2-31-20(27)13-16(26)14-32-22-24-19-6-4-3-5-18(19)21(28)25(22)12-11-15-7-9-17(10-8-15)33(23,29)30/h3-10H,2,11-14H2,1H3,(H2,23,29,30)

InChI Key

CIOVDYCHKJDFPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05024078

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.57

Hydrogen Bond Acceptors Count

14.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.424

Distribution Coefficient, logD

1.423

Water Solubility, LogSw

-2.36

Polar Surface Area

109.538

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

-0.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

K284-1365 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K284-1365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1365?
Check Price and Availability of K284-1365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-1365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1365 available by request