K284-1674 Screening compound: methyl 2-{[(2-methyl-1,3-thiazol-4-yl)methyl]sulfanyl}-3-(2-morpholinoethyl)-4-oxo-3,4-dihydro-7-quinazolinecarboxylate

K284-1674 Screening compound: methyl 2-{[(2-methyl-1,3-thiazol-4-yl)methyl]sulfanyl}-3-(2-morpholinoethyl)-4-oxo-3,4-dihydro-7-quinazolinecarboxylate
K284-1674 Screening compound: methyl 2-{[(2-methyl-1,3-thiazol-4-yl)methyl]sulfanyl}-3-(2-morpholinoethyl)-4-oxo-3,4-dihydro-7-quinazolinecarboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1674
methyl 2-{[(2-methyl-1,3-thiazol-4-yl)methyl]sulfanyl}-3-(2-morpholinoethyl)-4-oxo-3,4-dihydro-7-quinazolinecarboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1674

Molecular Formula

C21H24N4O4S2 (C21 H24 N4 O4 S2)

Compound Name

methyl 2-{[(2-methyl-1,3-thiazol-4-yl)methyl]sulfanyl}-3-(2-morpholinoethyl)-4-oxo-3,4-dihydro-7-quinazolinecarboxylate

IUPAC name

methyl 2-{[(2-methyl-13-thiazol-4-yl)methyl]sulfanyl}-3-[2-(morpholin-4-yl)ethyl]-4-oxo-34-dihydroquinazoline-7-carboxylate

SMILES

Cc1nc(CSC(N2CCN3CCOCC3)=Nc(cc(cc3)C(OC)=O)c3C2=O)cs1

InChI

InChI=1S/C21H24N4O4S2/c1-14-22-16(12-30-14)13-31-21-23-18-11-15(20(27)28-2)3-4-17(18)19(26)25(21)6-5-24-7-9-29-10-8-24/h3-4,11-12H,5-10,13H2,1-2H3

InChI Key

BCUMEXTUUAUZNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15087673

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.58

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.620

Distribution Coefficient, logD

2.556

Water Solubility, LogSw

-3.01

Polar Surface Area

69.121

Acid Dissociation Constant (pKa)

29.12

Base Dissociation Constant (pKb)

6.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.86

K284-1674 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K284-1674 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1674?
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What is the minimum amount of K284-1674 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1674
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1674
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1674 available by request