K284-1814 Screening compound: 7-(4-cyclohexylpiperazine-1-carbonyl)-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

K284-1814 Screening compound: 7-(4-cyclohexylpiperazine-1-carbonyl)-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
K284-1814 Screening compound: 7-(4-cyclohexylpiperazine-1-carbonyl)-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1814
7-(4-cyclohexylpiperazine-1-carbonyl)-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1814

Molecular Formula

C24H32N4O3S (C24 H32 N4 O3 S)

Compound Name

7-(4-cyclohexylpiperazine-1-carbonyl)-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

IUPAC name

7-(4-cyclohexylpiperazine-1-carbonyl)-3-[(oxolan-2-yl)methyl]-2-sulfanylidene-1234-tetrahydroquinazolin-4-one

SMILES

O=C(c(cc1)cc(NC(N2CC3OCCC3)=S)c1C2=O)N(CC1)CCN1C1CCCCC1

InChI

InChI=1S/C24H32N4O3S/c29-22(27-12-10-26(11-13-27)18-5-2-1-3-6-18)17-8-9-20-21(15-17)25-24(32)28(23(20)30)16-19-7-4-14-31-19/h8-9,15,18-19H,1-7,10-14,16H2,(H,25,32)/t19-/m1/s1

InChI Key

SAEYSQYCVMUMNC-LJQANCHMSA-N

MDL Number (MFCD)

MFCD04063082

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.61

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.507

Distribution Coefficient, logD

2.344

Water Solubility, LogSw

-3.08

Polar Surface Area

55.714

Acid Dissociation Constant (pKa)

10.33

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

62.50

K284-1814 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K284-1814 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1814?
Check Price and Availability of K284-1814, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-1814 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1814
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1814
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1814 available by request