K284-1992 Screening compound: ETHYL 4-[(4-{[4-OXO-2-THIOXO-1,4-DIHYDRO-3(2H)-QUINAZOLINYL]METHYL}CYCLOHEXYL)CARBONYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE

K284-1992 Screening compound: ETHYL 4-[(4-{[4-OXO-2-THIOXO-1,4-DIHYDRO-3(2H)-QUINAZOLINYL]METHYL}CYCLOHEXYL)CARBONYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE
K284-1992 Screening compound: ETHYL 4-[(4-{[4-OXO-2-THIOXO-1,4-DIHYDRO-3(2H)-QUINAZOLINYL]METHYL}CYCLOHEXYL)CARBONYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-1992
ETHYL 4-[(4-{[4-OXO-2-THIOXO-1,4-DIHYDRO-3(2H)-QUINAZOLINYL]METHYL}CYCLOHEXYL)CARBONYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-1992

Molecular Formula

C23H30N4O4S (C23 H30 N4 O4 S)

Compound Name

ETHYL 4-[(4-{[4-OXO-2-THIOXO-1,4-DIHYDRO-3(2H)-QUINAZOLINYL]METHYL}CYCLOHEXYL)CARBONYL]TETRAHYDRO-1(2H)-PYRAZINECARBOXYLATE

IUPAC name

n/a

SMILES

CCOC(N(CC1)CCN1C(C1CCC(CN(C(c(cccc2)c2N2)=O)C2=S)CC1)=O)=O

InChI

InChI=1S/C23H30N4O4S/c1-2-31-23(30)26-13-11-25(12-14-26)20(28)17-9-7-16(8-10-17)15-27-21(29)18-5-3-4-6-19(18)24-22(27)32/h3-6,16-17H,2,7-15H2,1H3,(H,24,32)

InChI Key

NGQCWZMNIAGKSH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05987972

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.665

Distribution Coefficient, logD

3.664

Water Solubility, LogSw

-3.95

Polar Surface Area

66.938

Acid Dissociation Constant (pKa)

9.99

Base Dissociation Constant (pKb)

3.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.50

K284-1992 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Kinases Annotated Library (2415 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with K284-1992 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-1992?
Check Price and Availability of K284-1992, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-1992 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-1992
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-1992
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-1992 available by request