K284-2084 Screening compound: methyl 2-({2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-4-oxo-3-[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxylate

K284-2084 Screening compound: methyl 2-({2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-4-oxo-3-[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxylate
K284-2084 Screening compound: methyl 2-({2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-4-oxo-3-[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-2084
methyl 2-({2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-4-oxo-3-[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-2084

Molecular Formula

C28H32N4O6S (C28 H32 N4 O6 S)

Compound Name

methyl 2-({2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-4-oxo-3-[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxylate

IUPAC name

methyl 2-({2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}sulfanyl)-4-oxo-3-[(oxolan-2-yl)methyl]-34-dihydroquinazoline-7-carboxylate

SMILES

COC(c(cc1)cc(N=C(N2CC3OCCC3)SCC(N(CC3)CCN3c(cccc3)c3OC)=O)c1C2=O)=O

InChI

InChI=1S/C28H32N4O6S/c1-36-24-8-4-3-7-23(24)30-11-13-31(14-12-30)25(33)18-39-28-29-22-16-19(27(35)37-2)9-10-21(22)26(34)32(28)17-20-6-5-15-38-20/h3-4,7-10,16,20H,5-6,11-15,17-18H2,1-2H3/t20-/m1/s1

InChI Key

HGPUYEMKLIYYJA-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD04421645

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

552.65

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.799

Distribution Coefficient, logD

2.799

Water Solubility, LogSw

-3.32

Polar Surface Area

82.581

Acid Dissociation Constant (pKa)

26.48

Base Dissociation Constant (pKb)

3.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

K284-2084 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K284-2084 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-2084?
Check Price and Availability of K284-2084, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-2084 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-2084
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-2084
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-2084 available by request