K284-3455 Screening compound: ethyl 4-(2-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate

K284-3455 Screening compound: ethyl 4-(2-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate
K284-3455 Screening compound: ethyl 4-(2-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-3455
ethyl 4-(2-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-3455

Molecular Formula

C24H32N4O4S (C24 H32 N4 O4 S)

Compound Name

ethyl 4-(2-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)piperidine-1-carboxylate

IUPAC name

ethyl 4-(2-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-4-oxo-34-dihydroquinazolin-3-yl)piperidine-1-carboxylate

SMILES

CCOC(N(CC1)CCC1N1C(SCC(N2CCC(C)CC2)=O)=Nc(cccc2)c2C1=O)=O

InChI

InChI=1S/C24H32N4O4S/c1-3-32-24(31)27-14-10-18(11-15-27)28-22(30)19-6-4-5-7-20(19)25-23(28)33-16-21(29)26-12-8-17(2)9-13-26/h4-7,17-18H,3,8-16H2,1-2H3

InChI Key

ZWPDDUZXEFQXIV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05024608

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.61

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.177

Distribution Coefficient, logD

3.177

Water Solubility, LogSw

-3.66

Polar Surface Area

64.165

Acid Dissociation Constant (pKa)

26.31

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.30

K284-3455 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with K284-3455 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-3455?
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What is the minimum amount of K284-3455 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-3455
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-3455
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-3455 available by request