K284-4148 Screening compound: 6-bromo-3-[6-oxo-6-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)hexyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

K284-4148 Screening compound: 6-bromo-3-[6-oxo-6-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)hexyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
K284-4148 Screening compound: 6-bromo-3-[6-oxo-6-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)hexyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-4148
6-bromo-3-[6-oxo-6-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)hexyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-4148

Molecular Formula

C25H26BrN3O2S (C25 H26 BrN3 O2 S)

Compound Name

6-bromo-3-[6-oxo-6-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)hexyl]-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

IUPAC name

6-bromo-3-[6-oxo-6-(4-phenyl-1236-tetrahydropyridin-1-yl)hexyl]-2-sulfanylidene-1234-tetrahydroquinazolin-4-one

SMILES

O=C(CCCCCN(C(c(cc(cc1)Br)c1N1)=O)C1=S)N(CC1)CC=C1c1ccccc1

InChI

InChI=1S/C25H26BrN3O2S/c26-20-10-11-22-21(17-20)24(31)29(25(32)27-22)14-6-2-5-9-23(30)28-15-12-19(13-16-28)18-7-3-1-4-8-18/h1,3-4,7-8,10-12,17H,2,5-6,9,13-16H2,(H,27,32)

InChI Key

KEAGJXQNWQUAQZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15088104

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

512.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.471

Distribution Coefficient, logD

5.406

Water Solubility, LogSw

-5.65

Polar Surface Area

43.417

Acid Dissociation Constant (pKa)

8.19

Base Dissociation Constant (pKb)

-2.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

K284-4148 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-4148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-4148?
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What is the minimum amount of K284-4148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-4148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-4148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-4148 available by request