K284-4430 Screening compound: 2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3,4-dihydroquinazolin-4-one

K284-4430 Screening compound: 2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3,4-dihydroquinazolin-4-one
K284-4430 Screening compound: 2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-4430
2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-4430

Molecular Formula

C28H28Cl2N4OS (C28 H28 Cl2 N4 OS)

Compound Name

2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3,4-dihydroquinazolin-4-one

IUPAC name

2-{[(2-chlorophenyl)methyl]sulfanyl}-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-34-dihydroquinazolin-4-one

SMILES

O=C1N(CCCN(CC2)CCN2c2cc(Cl)ccc2)C(SCc(cccc2)c2Cl)=Nc2c1cccc2

InChI

InChI=1S/C28H28Cl2N4OS/c29-22-8-5-9-23(19-22)33-17-15-32(16-18-33)13-6-14-34-27(35)24-10-2-4-12-26(24)31-28(34)36-20-21-7-1-3-11-25(21)30/h1-5,7-12,19H,6,13-18,20H2

InChI Key

ZDKZBCWLEHKDQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15088257

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

539.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.918

Distribution Coefficient, logD

5.783

Water Solubility, LogSw

-6.04

Polar Surface Area

32.992

Acid Dissociation Constant (pKa)

27.84

Base Dissociation Constant (pKb)

6.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

K284-4430 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • GPCR
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K284-4430 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-4430?
Check Price and Availability of K284-4430, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-4430 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-4430
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-4430
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-4430 available by request