K284-4571 Screening compound: 2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-4-oxo-N,3-bis[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxamide

K284-4571 Screening compound: 2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-4-oxo-N,3-bis[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxamide
K284-4571 Screening compound: 2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-4-oxo-N,3-bis[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-4571
2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-4-oxo-N,3-bis[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-4571

Molecular Formula

C27H28FN3O5S (C27 H28 FN3 O5 S)

Compound Name

2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-4-oxo-N,3-bis[(oxolan-2-yl)methyl]-3,4-dihydroquinazoline-7-carboxamide

IUPAC name

2-{[2-(4-fluorophenyl)-2-oxoethyl]sulfanyl}-4-oxo-N3-bis[(oxolan-2-yl)methyl]-34-dihydroquinazoline-7-carboxamide

SMILES

O=C(CSC(N1CC2OCCC2)=Nc(cc(cc2)C(NCC3OCCC3)=O)c2C1=O)c(cc1)ccc1F

InChI

InChI=1S/C27H28FN3O5S/c28-19-8-5-17(6-9-19)24(32)16-37-27-30-23-13-18(25(33)29-14-20-3-1-11-35-20)7-10-22(23)26(34)31(27)15-21-4-2-12-36-21/h5-10,13,20-21H,1-4,11-12,14-16H2,(H,29,33)

InChI Key

QGVYKGQJFUSMDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15088353

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

525.6

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.133

Distribution Coefficient, logD

2.133

Water Solubility, LogSw

-3.00

Polar Surface Area

80.740

Acid Dissociation Constant (pKa)

12.62

Base Dissociation Constant (pKb)

0.31

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

40.70

K284-4571 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-4571 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-4571?
Check Price and Availability of K284-4571, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-4571 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-4571
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-4571
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-4571 available by request