K284-6379 Screening compound: 6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]-N-[2-(4-sulfamoylphenyl)ethyl]hexanamide

Chemical Structure Depiction of ChemDiv screening compound K284-6379
6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]-N-[2-(4-sulfamoylphenyl)ethyl]hexanamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-6379

Molecular Formula

C₂₆H₃₃N₅O₅S₂ (C26 H33 N5 O5 S2)

Compound Name

6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-3-yl]-N-[2-(4-sulfamoylphenyl)ethyl]hexanamide

IUPAC name

6-[6-(morpholin-4-yl)-4-oxo-2-sulfanylidene-1234-tetrahydroquinazolin-3-yl]-N-[2-(4-sulfamoylphenyl)ethyl]hexanamide

SMILES

NS(c1ccc(CCNC(CCCCCN(C(c(cc(cc2)N3CCOCC3)c2N2)=O)C2=S)=O)cc1)(=O)=O

InChI

InChI=1S/C26H33N5O5S2/c27-38(34,35)21-8-5-19(6-9-21)11-12-28-24(32)4-2-1-3-13-31-25(33)22-18-20(30-14-16-36-17-15-30)7-10-23(22)29-26(31)37/h5-10,18H,1-4,11-17H2,(H,28,32)(H,29,37)(H2,27,34,35)

InChI Key

NISCQFXNIIZWIU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089300

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

559.71

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

12.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

1.086

Distribution Coefficient, logD

1.084

Water Solubility, LogSw

-2.44

Polar Surface Area

113.573

Acid Dissociation Constant (pK_a)

9.81

Base Dissociation Constant (pK_b)

1.74

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

42.30

K284-6379 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Eccentric PPI Library (11937 compounds)

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Antiviral
Infections
Immune system
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Male
Female
Hemic and lymphatic
Skin
Antiviral
Infections
Immune system
Cancer
Nervous system
Male
Female
Hemic and lymphatic
Skin
Endocrine

Mechanism of action:

PPI modulators
PPI modulators

Structure:

Cyclic compounds

Targets:

Kinases
Kinases
Phosphatases

References: we are preparing a list of scientific research reports with K284-6379 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-6379?
Check Price and Availability of K284-6379, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of K284-6379 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for K284-6379
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for K284-6379

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-6379 available by request