K284-6425 Screening compound: 6-(morpholin-4-yl)-3-(6-oxo-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}hexyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

K284-6425 Screening compound: 6-(morpholin-4-yl)-3-(6-oxo-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}hexyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
K284-6425 Screening compound: 6-(morpholin-4-yl)-3-(6-oxo-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}hexyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-6425
6-(morpholin-4-yl)-3-(6-oxo-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}hexyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-6425

Molecular Formula

C29H34F3N5O3S (C29 H34 F3 N5 O3 S)

Compound Name

6-(morpholin-4-yl)-3-(6-oxo-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}hexyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one

IUPAC name

6-(morpholin-4-yl)-3-(6-oxo-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}hexyl)-2-sulfanylidene-1234-tetrahydroquinazolin-4-one

SMILES

O=C(CCCCCN(C(c(cc(cc1)N2CCOCC2)c1N1)=O)C1=S)N(CC1)CCN1c1cc(C(F)(F)F)ccc1

InChI

InChI=1S/C29H34F3N5O3S/c30-29(31,32)21-5-4-6-22(19-21)34-11-13-36(14-12-34)26(38)7-2-1-3-10-37-27(39)24-20-23(35-15-17-40-18-16-35)8-9-25(24)33-28(37)41/h4-6,8-9,19-20H,1-3,7,10-18H2,(H,33,41)

InChI Key

RWQRGZPPNLJVET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089313

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

589.68

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.092

Distribution Coefficient, logD

4.090

Water Solubility, LogSw

-4.09

Polar Surface Area

58.310

Acid Dissociation Constant (pKa)

9.81

Base Dissociation Constant (pKb)

2.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.30

K284-6425 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-6425 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-6425?
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What is the minimum amount of K284-6425 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-6425
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-6425
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-6425 available by request