K284-7277 Screening compound: 4-[(2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-N-cyclopropylbenzamide

K284-7277 Screening compound: 4-[(2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-N-cyclopropylbenzamide
K284-7277 Screening compound: 4-[(2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-N-cyclopropylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-7277
4-[(2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-N-cyclopropylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-7277

Molecular Formula

C26H21ClFN3O2S (C26 H21 ClFN3 O2 S)

Compound Name

4-[(2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-oxo-3,4-dihydroquinazolin-3-yl)methyl]-N-cyclopropylbenzamide

IUPAC name

4-[(2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-4-oxo-34-dihydroquinazolin-3-yl)methyl]-N-cyclopropylbenzamide

SMILES

O=C(c1ccc(CN2C(SCc(c(F)ccc3)c3Cl)=Nc(cccc3)c3C2=O)cc1)NC1CC1

InChI

InChI=1S/C26H21ClFN3O2S/c27-21-5-3-6-22(28)20(21)15-34-26-30-23-7-2-1-4-19(23)25(33)31(26)14-16-8-10-17(11-9-16)24(32)29-18-12-13-18/h1-11,18H,12-15H2,(H,29,32)

InChI Key

RUJUWMDRMRGOCE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089559

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.99

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.959

Distribution Coefficient, logD

4.959

Water Solubility, LogSw

-5.04

Polar Surface Area

50.241

Acid Dissociation Constant (pKa)

12.24

Base Dissociation Constant (pKb)

0.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

K284-7277 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-7277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-7277?
Check Price and Availability of K284-7277, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-7277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-7277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-7277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-7277 available by request