K284-7467 Screening compound: N-(4-fluorophenyl)-2-[(3-{3-[2-({[(4-fluorophenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3,4-dihydroquinazolin-3-yl]propyl}-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide

K284-7467 Screening compound: N-(4-fluorophenyl)-2-[(3-{3-[2-({[(4-fluorophenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3,4-dihydroquinazolin-3-yl]propyl}-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide
K284-7467 Screening compound: N-(4-fluorophenyl)-2-[(3-{3-[2-({[(4-fluorophenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3,4-dihydroquinazolin-3-yl]propyl}-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-7467
N-(4-fluorophenyl)-2-[(3-{3-[2-({[(4-fluorophenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3,4-dihydroquinazolin-3-yl]propyl}-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-7467

Molecular Formula

C35H28F2N6O4S2 (C35 H28 F2 N6 O4 S2)

Compound Name

N-(4-fluorophenyl)-2-[(3-{3-[2-({[(4-fluorophenyl)carbamoyl]methyl}sulfanyl)-4-oxo-3,4-dihydroquinazolin-3-yl]propyl}-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetamide

IUPAC name

N-(4-fluorophenyl)-2-[(3-{3-[2-({[(4-fluorophenyl)carbamoyl]methyl}sulfanyl)-4-oxo-34-dihydroquinazolin-3-yl]propyl}-4-oxo-34-dihydroquinazolin-2-yl)sulfanyl]acetamide

SMILES

O=C(CSC(N1CCCN2C(SCC(Nc(cc3)ccc3F)=O)=Nc(cccc3)c3C2=O)=Nc(cccc2)c2C1=O)Nc(cc1)ccc1F

InChI

InChI=1S/C35H28F2N6O4S2/c36-22-10-14-24(15-11-22)38-30(44)20-48-34-40-28-8-3-1-6-26(28)32(46)42(34)18-5-19-43-33(47)27-7-2-4-9-29(27)41-35(43)49-21-31(45)39-25-16-12-23(37)13-17-25/h1-4,6-17H,5,18-21H2,(H,38,44)(H,39,45)

InChI Key

OEHSXJCEOSULPM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089690

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

698.77

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

14.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

4.865

Distribution Coefficient, logD

4.865

Water Solubility, LogSw

-4.70

Polar Surface Area

97.831

Acid Dissociation Constant (pKa)

11.22

Base Dissociation Constant (pKb)

0.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

K284-7467 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K284-7467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-7467?
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What is the minimum amount of K284-7467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-7467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-7467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-7467 available by request