K284-7527 Screening compound: 2-{[4-oxo-3-(3-{4-oxo-2-[({[4-(propan-2-yl)phenyl]carbamoyl}methyl)sulfanyl]-3,4-dihydroquinazolin-3-yl}propyl)-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide

K284-7527 Screening compound: 2-{[4-oxo-3-(3-{4-oxo-2-[({[4-(propan-2-yl)phenyl]carbamoyl}methyl)sulfanyl]-3,4-dihydroquinazolin-3-yl}propyl)-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide
K284-7527 Screening compound: 2-{[4-oxo-3-(3-{4-oxo-2-[({[4-(propan-2-yl)phenyl]carbamoyl}methyl)sulfanyl]-3,4-dihydroquinazolin-3-yl}propyl)-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-7527
2-{[4-oxo-3-(3-{4-oxo-2-[({[4-(propan-2-yl)phenyl]carbamoyl}methyl)sulfanyl]-3,4-dihydroquinazolin-3-yl}propyl)-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-7527

Molecular Formula

C41H42N6O4S2 (C41 H42 N6 O4 S2)

Compound Name

2-{[4-oxo-3-(3-{4-oxo-2-[({[4-(propan-2-yl)phenyl]carbamoyl}methyl)sulfanyl]-3,4-dihydroquinazolin-3-yl}propyl)-3,4-dihydroquinazolin-2-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide

IUPAC name

2-{[4-oxo-3-(3-{4-oxo-2-[({[4-(propan-2-yl)phenyl]carbamoyl}methyl)sulfanyl]-34-dihydroquinazolin-3-yl}propyl)-34-dihydroquinazolin-2-yl]sulfanyl}-N-[4-(propan-2-yl)phenyl]acetamide

SMILES

CC(C)c(cc1)ccc1NC(CSC(N1CCCN2C(SCC(Nc3ccc(C(C)C)cc3)=O)=Nc(cccc3)c3C2=O)=Nc(cccc2)c2C1=O)=O

InChI

InChI=1S/C41H42N6O4S2/c1-26(2)28-14-18-30(19-15-28)42-36(48)24-52-40-44-34-12-7-5-10-32(34)38(50)46(40)22-9-23-47-39(51)33-11-6-8-13-35(33)45-41(47)53-25-37(49)43-31-20-16-29(17-21-31)27(3)4/h5-8,10-21,26-27H,9,22-25H2,1-4H3,(H,42,48)(H,43,49)

InChI Key

CIASEGGCHAZWMC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089733

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

746.95

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

16.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

7.483

Distribution Coefficient, logD

7.483

Water Solubility, LogSw

-5.65

Polar Surface Area

97.831

Acid Dissociation Constant (pKa)

12.90

Base Dissociation Constant (pKb)

0.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.80

K284-7527 in Drug Discovery

Included in Screening Libraries

Regenerative Medicine Focused Library (23016 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with K284-7527 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-7527?
Check Price and Availability of K284-7527, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-7527 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-7527
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-7527
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-7527 available by request