K284-7829 Screening compound: ethyl 4-[5-oxo-2-(phenylamino)-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carbonyl]piperazine-1-carboxylate

K284-7829 Screening compound: ethyl 4-[5-oxo-2-(phenylamino)-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carbonyl]piperazine-1-carboxylate
K284-7829 Screening compound: ethyl 4-[5-oxo-2-(phenylamino)-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carbonyl]piperazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-7829
ethyl 4-[5-oxo-2-(phenylamino)-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carbonyl]piperazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-7829

Molecular Formula

C23H22N6O4S (C23 H22 N6 O4 S)

Compound Name

ethyl 4-[5-oxo-2-(phenylamino)-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carbonyl]piperazine-1-carboxylate

IUPAC name

ethyl 4-[5-oxo-2-(phenylamino)-5H-[134]thiadiazolo[23-b]quinazoline-8-carbonyl]piperazine-1-carboxylate

SMILES

CCOC(N(CC1)CCN1C(c(cc1)cc(N=C2SC(Nc3ccccc3)=NN22)c1C2=O)=O)=O

InChI

InChI=1S/C23H22N6O4S/c1-2-33-23(32)28-12-10-27(11-13-28)19(30)15-8-9-17-18(14-15)25-22-29(20(17)31)26-21(34-22)24-16-6-4-3-5-7-16/h3-9,14H,2,10-13H2,1H3,(H,24,26)

InChI Key

OTZRPFVMHOKTHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15089920

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.370

Distribution Coefficient, logD

2.365

Water Solubility, LogSw

-3.27

Polar Surface Area

86.295

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

4.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

K284-7829 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Receptors Annotated Library (5376 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K284-7829 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-7829?
Check Price and Availability of K284-7829, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-7829 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-7829
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-7829
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-7829 available by request