K284-7846 Screening compound: 5-oxo-2-(phenylamino)-N-[(thiophen-2-yl)methyl]-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxamide

K284-7846 Screening compound: 5-oxo-2-(phenylamino)-N-[(thiophen-2-yl)methyl]-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxamide
K284-7846 Screening compound: 5-oxo-2-(phenylamino)-N-[(thiophen-2-yl)methyl]-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K284-7846
5-oxo-2-(phenylamino)-N-[(thiophen-2-yl)methyl]-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K284-7846

Molecular Formula

C21H15N5O2S2 (C21 H15 N5 O2 S2)

Compound Name

5-oxo-2-(phenylamino)-N-[(thiophen-2-yl)methyl]-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxamide

IUPAC name

5-oxo-2-(phenylamino)-N-[(thiophen-2-yl)methyl]-5H-[134]thiadiazolo[23-b]quinazoline-8-carboxamide

SMILES

O=C(c(cc1)cc(N=C2SC(Nc3ccccc3)=NN22)c1C2=O)NCc1cccs1

InChI

InChI=1S/C21H15N5O2S2/c27-18(22-12-15-7-4-10-29-15)13-8-9-16-17(11-13)24-21-26(19(16)28)25-20(30-21)23-14-5-2-1-3-6-14/h1-11H,12H2,(H,22,27)(H,23,25)

InChI Key

BBOIWRCLFPLFMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08541396

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.476

Distribution Coefficient, logD

3.471

Water Solubility, LogSw

-3.91

Polar Surface Area

72.298

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

4.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

K284-7846 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Annotated Library (21441 compounds)

CNS targets activity set (6557 compounds)

Human GPCR Annotated Library (5539 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with K284-7846 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K284-7846?
Check Price and Availability of K284-7846, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K284-7846 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K284-7846
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K284-7846
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K284-7846 available by request