K286-0028 Screening compound: 5-{[(4-tert-butylphenyl)methyl]sulfanyl}-3,6-bis(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-0028 Screening compound: 5-{[(4-tert-butylphenyl)methyl]sulfanyl}-3,6-bis(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-0028 Screening compound: 5-{[(4-tert-butylphenyl)methyl]sulfanyl}-3,6-bis(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0028
5-{[(4-tert-butylphenyl)methyl]sulfanyl}-3,6-bis(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0028

Molecular Formula

C32H33N3OS3 (C32 H33 N3 OS3)

Compound Name

5-{[(4-tert-butylphenyl)methyl]sulfanyl}-3,6-bis(2,6-dimethylphenyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[(4-tert-butylphenyl)methyl]sulfanyl}-36-bis(26-dimethylphenyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CC(C)(C)c1ccc(CSC(N(C2=O)c3c(C)cccc3C)=NC(N3c4c(C)cccc4C)=C2SC3=S)cc1

InChI

InChI=1S/C32H33N3OS3/c1-19-10-8-11-20(2)25(19)34-28-27(39-31(34)37)29(36)35(26-21(3)12-9-13-22(26)4)30(33-28)38-18-23-14-16-24(17-15-23)32(5,6)7/h8-17H,18H2,1-7H3

InChI Key

RHUWBTILNKVHQU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02651558

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

571.83

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

8.599

Distribution Coefficient, logD

8.599

Water Solubility, LogSw

-5.77

Polar Surface Area

25.751

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.10

K286-0028 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0028?
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What is the minimum amount of K286-0028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0028 available by request