K286-0077 Screening compound: N-[(furan-2-yl)methyl]-2-({7-oxo-3,6-diphenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetamide

K286-0077 Screening compound: N-[(furan-2-yl)methyl]-2-({7-oxo-3,6-diphenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetamide
K286-0077 Screening compound: N-[(furan-2-yl)methyl]-2-({7-oxo-3,6-diphenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0077
N-[(furan-2-yl)methyl]-2-({7-oxo-3,6-diphenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0077

Molecular Formula

C24H18N4O3S3 (C24 H18 N4 O3 S3)

Compound Name

N-[(furan-2-yl)methyl]-2-({7-oxo-3,6-diphenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl}sulfanyl)acetamide

IUPAC name

N-[(furan-2-yl)methyl]-2-({7-oxo-36-diphenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl}sulfanyl)acetamide

SMILES

O=C(CSC(N(c1ccccc1)C1=O)=NC(N2c3ccccc3)=C1SC2=S)NCc1ccco1

InChI

InChI=1S/C24H18N4O3S3/c29-19(25-14-18-12-7-13-31-18)15-33-23-26-21-20(22(30)28(23)17-10-5-2-6-11-17)34-24(32)27(21)16-8-3-1-4-9-16/h1-13H,14-15H2,(H,25,29)

InChI Key

WTXAXXLYHGJZJN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02651579

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

506.63

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.096

Distribution Coefficient, logD

4.096

Water Solubility, LogSw

-4.25

Polar Surface Area

59.175

Acid Dissociation Constant (pKa)

13.42

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

K286-0077 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0077 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0077?
Check Price and Availability of K286-0077, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-0077 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0077
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0077
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0077 available by request