K286-0124 Screening compound: N-[(furan-2-yl)methyl]-2-{[6-(2-methoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

K286-0124 Screening compound: N-[(furan-2-yl)methyl]-2-{[6-(2-methoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide
K286-0124 Screening compound: N-[(furan-2-yl)methyl]-2-{[6-(2-methoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0124
N-[(furan-2-yl)methyl]-2-{[6-(2-methoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0124

Molecular Formula

C25H20N4O4S3 (C25 H20 N4 O4 S3)

Compound Name

N-[(furan-2-yl)methyl]-2-{[6-(2-methoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-[(furan-2-yl)methyl]-2-{[6-(2-methoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

COc(cccc1)c1N(C1=O)C(SCC(NCc2ccco2)=O)=NC(N2c3ccccc3)=C1SC2=S

InChI

InChI=1S/C25H20N4O4S3/c1-32-19-12-6-5-11-18(19)29-23(31)21-22(28(25(34)36-21)16-8-3-2-4-9-16)27-24(29)35-15-20(30)26-14-17-10-7-13-33-17/h2-13H,14-15H2,1H3,(H,26,30)

InChI Key

VMXIAUJHLLSKPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02651614

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

536.66

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.077

Distribution Coefficient, logD

4.077

Water Solubility, LogSw

-4.23

Polar Surface Area

66.504

Acid Dissociation Constant (pKa)

13.42

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

K286-0124 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0124 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0124?
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What is the minimum amount of K286-0124 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0124
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0124
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0124 available by request