K286-0342 Screening compound: ethyl 2-{[6-(2,4-dimethoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate

K286-0342 Screening compound: ethyl 2-{[6-(2,4-dimethoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate
K286-0342 Screening compound: ethyl 2-{[6-(2,4-dimethoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0342
ethyl 2-{[6-(2,4-dimethoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0342

Molecular Formula

C23H21N3O5S3 (C23 H21 N3 O5 S3)

Compound Name

ethyl 2-{[6-(2,4-dimethoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetate

IUPAC name

ethyl 2-{[6-(24-dimethoxyphenyl)-7-oxo-3-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetate

SMILES

CCOC(CSC(N(c(ccc(OC)c1)c1OC)C1=O)=NC(N2c3ccccc3)=C1SC2=S)=O

InChI

InChI=1S/C23H21N3O5S3/c1-4-31-18(27)13-33-22-24-20-19(34-23(32)25(20)14-8-6-5-7-9-14)21(28)26(22)16-11-10-15(29-2)12-17(16)30-3/h5-12H,4,13H2,1-3H3

InChI Key

LPNVGBFKILPMSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090083

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

515.63

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.082

Distribution Coefficient, logD

4.082

Water Solubility, LogSw

-4.24

Polar Surface Area

62.258

Acid Dissociation Constant (pKa)

29.82

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

K286-0342 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Human Kinases Annotated Library (2415 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0342 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0342?
Check Price and Availability of K286-0342, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K286-0342 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0342
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0342
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0342 available by request