K286-0344 Screening compound: 6-(2,4-dimethoxyphenyl)-5-[(3,3-dimethyl-2-oxobutyl)sulfanyl]-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-0344 Screening compound: 6-(2,4-dimethoxyphenyl)-5-[(3,3-dimethyl-2-oxobutyl)sulfanyl]-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-0344 Screening compound: 6-(2,4-dimethoxyphenyl)-5-[(3,3-dimethyl-2-oxobutyl)sulfanyl]-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0344
6-(2,4-dimethoxyphenyl)-5-[(3,3-dimethyl-2-oxobutyl)sulfanyl]-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0344

Molecular Formula

C25H25N3O4S3 (C25 H25 N3 O4 S3)

Compound Name

6-(2,4-dimethoxyphenyl)-5-[(3,3-dimethyl-2-oxobutyl)sulfanyl]-3-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

6-(24-dimethoxyphenyl)-5-[(33-dimethyl-2-oxobutyl)sulfanyl]-3-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CC(C)(C)C(CSC(N(c(ccc(OC)c1)c1OC)C1=O)=NC(N2c3ccccc3)=C1SC2=S)=O

InChI

InChI=1S/C25H25N3O4S3/c1-25(2,3)19(29)14-34-23-26-21-20(35-24(33)27(21)15-9-7-6-8-10-15)22(30)28(23)17-12-11-16(31-4)13-18(17)32-5/h6-13H,14H2,1-5H3

InChI Key

YCNINHOOCHJQLG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090084

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

527.69

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.999

Distribution Coefficient, logD

4.999

Water Solubility, LogSw

-4.71

Polar Surface Area

55.346

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

K286-0344 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Human Kinases Annotated Library (2415 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0344?
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What is the minimum amount of K286-0344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0344 available by request