K286-0487 Screening compound: 3-(2-ethoxyphenyl)-5-{[(oxolan-2-yl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-0487 Screening compound: 3-(2-ethoxyphenyl)-5-{[(oxolan-2-yl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-0487 Screening compound: 3-(2-ethoxyphenyl)-5-{[(oxolan-2-yl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0487
3-(2-ethoxyphenyl)-5-{[(oxolan-2-yl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0487

Molecular Formula

C24H23N3O3S3 (C24 H23 N3 O3 S3)

Compound Name

3-(2-ethoxyphenyl)-5-{[(oxolan-2-yl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(2-ethoxyphenyl)-5-{[(oxolan-2-yl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CCOc(cccc1)c1N(C(N=C(N(c1ccccc1)C1=O)SCC2OCCC2)=C1S1)C1=S

InChI

InChI=1S/C24H23N3O3S3/c1-2-29-19-13-7-6-12-18(19)27-21-20(33-24(27)31)22(28)26(16-9-4-3-5-10-16)23(25-21)32-15-17-11-8-14-30-17/h3-7,9-10,12-13,17H,2,8,11,14-15H2,1H3/t17-/m1/s1

InChI Key

YHTIDJHVHJCVJO-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD15090118

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.66

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.350

Distribution Coefficient, logD

4.350

Water Solubility, LogSw

-4.24

Polar Surface Area

42.518

Acid Dissociation Constant (pKa)

26.64

Base Dissociation Constant (pKb)

-4.32

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.20

K286-0487 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0487?
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What is the minimum amount of K286-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0487 available by request