K286-0496 Screening compound: 2-{[3-(2-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

K286-0496 Screening compound: 2-{[3-(2-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide
K286-0496 Screening compound: 2-{[3-(2-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0496
2-{[3-(2-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0496

Molecular Formula

C24H19N5O3S4 (C24 H19 N5 O3 S4)

Compound Name

2-{[3-(2-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

IUPAC name

2-{[3-(2-ethoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}-N-(13-thiazol-2-yl)acetamide

SMILES

CCOc(cccc1)c1N(C(N=C(N(c1ccccc1)C1=O)SCC(Nc2nccs2)=O)=C1S1)C1=S

InChI

InChI=1S/C24H19N5O3S4/c1-2-32-17-11-7-6-10-16(17)29-20-19(36-24(29)33)21(31)28(15-8-4-3-5-9-15)23(27-20)35-14-18(30)26-22-25-12-13-34-22/h3-13H,2,14H2,1H3,(H,25,26,30)

InChI Key

ZZOBZXMYFQHZGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090126

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

553.71

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.275

Distribution Coefficient, logD

4.274

Water Solubility, LogSw

-4.21

Polar Surface Area

67.492

Acid Dissociation Constant (pKa)

10.64

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

K286-0496 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0496 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0496?
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What is the minimum amount of K286-0496 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0496
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0496
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0496 available by request