K286-0790 Screening compound: N-(2,4-dimethoxyphenyl)-2-{[3-(3-methoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

K286-0790 Screening compound: N-(2,4-dimethoxyphenyl)-2-{[3-(3-methoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide
K286-0790 Screening compound: N-(2,4-dimethoxyphenyl)-2-{[3-(3-methoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0790
N-(2,4-dimethoxyphenyl)-2-{[3-(3-methoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0790

Molecular Formula

C28H24N4O5S3 (C28 H24 N4 O5 S3)

Compound Name

N-(2,4-dimethoxyphenyl)-2-{[3-(3-methoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-(24-dimethoxyphenyl)-2-{[3-(3-methoxyphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

COc1cccc(N(C(N=C(N(c2ccccc2)C2=O)SCC(Nc(ccc(OC)c3)c3OC)=O)=C2S2)C2=S)c1

InChI

InChI=1S/C28H24N4O5S3/c1-35-19-11-7-10-18(14-19)31-25-24(40-28(31)38)26(34)32(17-8-5-4-6-9-17)27(30-25)39-16-23(33)29-21-13-12-20(36-2)15-22(21)37-3/h4-15H,16H2,1-3H3,(H,29,33)

InChI Key

PEJWONWAMHEATN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090157

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

592.72

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.695

Distribution Coefficient, logD

4.695

Water Solubility, LogSw

-4.48

Polar Surface Area

72.124

Acid Dissociation Constant (pKa)

11.34

Base Dissociation Constant (pKb)

1.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

K286-0790 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0790 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0790?
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What is the minimum amount of K286-0790 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0790
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0790
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0790 available by request