K286-0872 Screening compound: 6-(2-methoxyphenyl)-3-(3-methoxyphenyl)-5-{[(pyridin-3-yl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-0872 Screening compound: 6-(2-methoxyphenyl)-3-(3-methoxyphenyl)-5-{[(pyridin-3-yl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-0872 Screening compound: 6-(2-methoxyphenyl)-3-(3-methoxyphenyl)-5-{[(pyridin-3-yl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0872
6-(2-methoxyphenyl)-3-(3-methoxyphenyl)-5-{[(pyridin-3-yl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0872

Molecular Formula

C25H20N4O3S3 (C25 H20 N4 O3 S3)

Compound Name

6-(2-methoxyphenyl)-3-(3-methoxyphenyl)-5-{[(pyridin-3-yl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

6-(2-methoxyphenyl)-3-(3-methoxyphenyl)-5-{[(pyridin-3-yl)methyl]sulfanyl}-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

COc1cccc(N(C(N=C(N(c(cccc2)c2OC)C2=O)SCc3cnccc3)=C2S2)C2=S)c1

InChI

InChI=1S/C25H20N4O3S3/c1-31-18-9-5-8-17(13-18)28-22-21(35-25(28)33)23(30)29(19-10-3-4-11-20(19)32-2)24(27-22)34-15-16-7-6-12-26-14-16/h3-14H,15H2,1-2H3

InChI Key

AGRBXVPDRFQKRR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090162

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

520.66

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.243

Distribution Coefficient, logD

4.231

Water Solubility, LogSw

-4.23

Polar Surface Area

51.346

Acid Dissociation Constant (pKa)

31.52

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

K286-0872 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0872 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0872?
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What is the minimum amount of K286-0872 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0872
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0872
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0872 available by request