K286-0912 Screening compound: 2-{[6-(4-ethoxyphenyl)-3-(3-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

K286-0912 Screening compound: 2-{[6-(4-ethoxyphenyl)-3-(3-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide
K286-0912 Screening compound: 2-{[6-(4-ethoxyphenyl)-3-(3-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-0912
2-{[6-(4-ethoxyphenyl)-3-(3-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-0912

Molecular Formula

C25H21N5O4S4 (C25 H21 N5 O4 S4)

Compound Name

2-{[6-(4-ethoxyphenyl)-3-(3-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide

IUPAC name

2-{[6-(4-ethoxyphenyl)-3-(3-methoxyphenyl)-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}-N-(13-thiazol-2-yl)acetamide

SMILES

CCOc(cc1)ccc1N(C1=O)C(SCC(Nc2nccs2)=O)=NC(N2c3cc(OC)ccc3)=C1SC2=S

InChI

InChI=1S/C25H21N5O4S4/c1-3-34-17-9-7-15(8-10-17)30-22(32)20-21(28-24(30)37-14-19(31)27-23-26-11-12-36-23)29(25(35)38-20)16-5-4-6-18(13-16)33-2/h4-13H,3,14H2,1-2H3,(H,26,27,31)

InChI Key

KRQFVAYNEBORBH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090184

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

583.74

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.606

Distribution Coefficient, logD

4.606

Water Solubility, LogSw

-4.40

Polar Surface Area

75.250

Acid Dissociation Constant (pKa)

10.64

Base Dissociation Constant (pKb)

-9.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

K286-0912 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-0912 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-0912?
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What is the minimum amount of K286-0912 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-0912
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-0912
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-0912 available by request