K286-1918 Screening compound: N-[4-(dimethylamino)phenyl]-2-{[3-(4-ethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

K286-1918 Screening compound: N-[4-(dimethylamino)phenyl]-2-{[3-(4-ethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide
K286-1918 Screening compound: N-[4-(dimethylamino)phenyl]-2-{[3-(4-ethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-1918
N-[4-(dimethylamino)phenyl]-2-{[3-(4-ethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-1918

Molecular Formula

C29H27N5O2S3 (C29 H27 N5 O2 S3)

Compound Name

N-[4-(dimethylamino)phenyl]-2-{[3-(4-ethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-[4-(dimethylamino)phenyl]-2-{[3-(4-ethylphenyl)-7-oxo-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

CCc(cc1)ccc1N(C(N=C(N(c1ccccc1)C1=O)SCC(Nc(cc2)ccc2N(C)C)=O)=C1S1)C1=S

InChI

InChI=1S/C29H27N5O2S3/c1-4-19-10-14-23(15-11-19)33-26-25(39-29(33)37)27(36)34(22-8-6-5-7-9-22)28(31-26)38-18-24(35)30-20-12-16-21(17-13-20)32(2)3/h5-17H,4,18H2,1-3H3,(H,30,35)

InChI Key

GMAGJXQUQNIIDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090349

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

573.76

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.807

Distribution Coefficient, logD

5.798

Water Solubility, LogSw

-5.46

Polar Surface Area

52.909

Acid Dissociation Constant (pKa)

12.94

Base Dissociation Constant (pKb)

9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.20

K286-1918 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-1918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-1918?
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What is the minimum amount of K286-1918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-1918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-1918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-1918 available by request