K286-3216 Screening compound: 3-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3216 Screening compound: 3-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3216 Screening compound: 3-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3216
3-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3216

Molecular Formula

C19H13ClFN3O2S3 (C19 H13 ClFN3 O2 S3)

Compound Name

3-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(5-chloro-2-methoxyphenyl)-6-(4-fluorophenyl)-5-(methylsulfanyl)-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

COc(ccc(Cl)c1)c1N(C(N=C(N(c(cc1)ccc1F)C1=O)SC)=C1S1)C1=S

InChI

InChI=1S/C19H13ClFN3O2S3/c1-26-14-8-3-10(20)9-13(14)24-16-15(29-19(24)27)17(25)23(18(22-16)28-2)12-6-4-11(21)5-7-12/h3-9H,1-2H3

InChI Key

KFZFFYPUEOVXHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090466

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.98

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.472

Distribution Coefficient, logD

4.472

Water Solubility, LogSw

-4.66

Polar Surface Area

34.556

Acid Dissociation Constant (pKa)

32.90

Base Dissociation Constant (pKb)

-10.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

K286-3216 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3216 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3216?
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What is the minimum amount of K286-3216 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3216
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3216
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3216 available by request