K286-3505 Screening compound: 3-[2-(diethylamino)ethyl]-6-(2-methoxyphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3505 Screening compound: 3-[2-(diethylamino)ethyl]-6-(2-methoxyphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3505 Screening compound: 3-[2-(diethylamino)ethyl]-6-(2-methoxyphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3505
3-[2-(diethylamino)ethyl]-6-(2-methoxyphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3505

Molecular Formula

C26H30N4O2S3 (C26 H30 N4 O2 S3)

Compound Name

3-[2-(diethylamino)ethyl]-6-(2-methoxyphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-[2-(diethylamino)ethyl]-6-(2-methoxyphenyl)-5-{[(2-methylphenyl)methyl]sulfanyl}-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CCN(CC)CCN(C(N=C(N(c(cccc1)c1OC)C1=O)SCc2c(C)cccc2)=C1S1)C1=S

InChI

InChI=1S/C26H30N4O2S3/c1-5-28(6-2)15-16-29-23-22(35-26(29)33)24(31)30(20-13-9-10-14-21(20)32-4)25(27-23)34-17-19-12-8-7-11-18(19)3/h7-14H,5-6,15-17H2,1-4H3

InChI Key

YHUIPKFTARGIFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090585

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

526.75

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.758

Distribution Coefficient, logD

3.884

Water Solubility, LogSw

-5.38

Polar Surface Area

38.557

Acid Dissociation Constant (pKa)

28.43

Base Dissociation Constant (pKb)

9.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

K286-3505 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3505 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3505?
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What is the minimum amount of K286-3505 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3505
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3505
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3505 available by request