K286-3516 Screening compound: 5-[(2-chlorobenzyl)sulfanyl]-3-(2-methylphenyl)[1,3]thiazolo[4',5':4,5]pyrimido[1,6-a][1,3]benzimidazole-2(3H)-thione

K286-3516 Screening compound: 5-[(2-chlorobenzyl)sulfanyl]-3-(2-methylphenyl)[1,3]thiazolo[4',5':4,5]pyrimido[1,6-a][1,3]benzimidazole-2(3H)-thione
K286-3516 Screening compound: 5-[(2-chlorobenzyl)sulfanyl]-3-(2-methylphenyl)[1,3]thiazolo[4',5':4,5]pyrimido[1,6-a][1,3]benzimidazole-2(3H)-thione alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3516
5-[(2-chlorobenzyl)sulfanyl]-3-(2-methylphenyl)[1,3]thiazolo[4',5':4,5]pyrimido[1,6-a][1,3]benzimidazole-2(3H)-thione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3516

Molecular Formula

C25H17ClN4S3 (C25 H17 ClN4 S3)

Compound Name

5-[(2-chlorobenzyl)sulfanyl]-3-(2-methylphenyl)[1,3]thiazolo[4',5':4,5]pyrimido[1,6-a][1,3]benzimidazole-2(3H)-thione

IUPAC name

8-{[(2-chlorophenyl)methyl]sulfanyl}-5-(2-methylphenyl)-3-thia-57916-tetraazatetracyclo[7.7.0.0^{26}.0^{1015}]hexadeca-1(16)2(6)710(15)1113-hexaene-4-thione

SMILES

Cc(cccc1)c1N(c(nc(n1c2nc3c1cccc3)SCc(cccc1)c1Cl)c2S1)C1=S

InChI

InChI=1S/C25H17ClN4S3/c1-15-8-2-6-12-19(15)30-23-21(33-25(30)31)22-27-18-11-5-7-13-20(18)29(22)24(28-23)32-14-16-9-3-4-10-17(16)26/h2-13H,14H2,1H3

InChI Key

PJQPAZIQPBRYEL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD02935309

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

505.09

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

7.136

Distribution Coefficient, logD

7.136

Water Solubility, LogSw

-6.52

Polar Surface Area

22.350

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

K286-3516 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K286-3516 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3516?
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What is the minimum amount of K286-3516 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3516
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3516
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3516 available by request