K286-3547 Screening compound: N-benzyl-2-{[3-(4-ethylphenyl)-6-(2-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

K286-3547 Screening compound: N-benzyl-2-{[3-(4-ethylphenyl)-6-(2-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide
K286-3547 Screening compound: N-benzyl-2-{[3-(4-ethylphenyl)-6-(2-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3547
N-benzyl-2-{[3-(4-ethylphenyl)-6-(2-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3547

Molecular Formula

C29H26N4O3S3 (C29 H26 N4 O3 S3)

Compound Name

N-benzyl-2-{[3-(4-ethylphenyl)-6-(2-methoxyphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-benzyl-2-{[3-(4-ethylphenyl)-6-(2-methoxyphenyl)-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

CCc(cc1)ccc1N(C(N=C(N(c(cccc1)c1OC)C1=O)SCC(NCc2ccccc2)=O)=C1S1)C1=S

InChI

InChI=1S/C29H26N4O3S3/c1-3-19-13-15-21(16-14-19)32-26-25(39-29(32)37)27(35)33(22-11-7-8-12-23(22)36-2)28(31-26)38-18-24(34)30-17-20-9-5-4-6-10-20/h4-16H,3,17-18H2,1-2H3,(H,30,34)

InChI Key

GLBLDVFKSIQRDE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090593

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

574.75

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.379

Distribution Coefficient, logD

5.379

Water Solubility, LogSw

-5.36

Polar Surface Area

58.755

Acid Dissociation Constant (pKa)

13.60

Base Dissociation Constant (pKb)

-9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.20

K286-3547 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3547 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3547?
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What is the minimum amount of K286-3547 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3547
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3547
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3547 available by request