K286-3630 Screening compound: 3-(4-ethylphenyl)-6-(2-methylphenyl)-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3630 Screening compound: 3-(4-ethylphenyl)-6-(2-methylphenyl)-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3630 Screening compound: 3-(4-ethylphenyl)-6-(2-methylphenyl)-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3630
3-(4-ethylphenyl)-6-(2-methylphenyl)-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3630

Molecular Formula

C28H30N4O2S3 (C28 H30 N4 O2 S3)

Compound Name

3-(4-ethylphenyl)-6-(2-methylphenyl)-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(4-ethylphenyl)-6-(2-methylphenyl)-5-{[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl}-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CCc(cc1)ccc1N(C(N=C(N(c1c(C)cccc1)C1=O)SCC(N2CCC(C)CC2)=O)=C1S1)C1=S

InChI

InChI=1S/C28H30N4O2S3/c1-4-20-9-11-21(12-10-20)31-25-24(37-28(31)35)26(34)32(22-8-6-5-7-19(22)3)27(29-25)36-17-23(33)30-15-13-18(2)14-16-30/h5-12,18H,4,13-17H2,1-3H3

InChI Key

PBJYPCODDZDJRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090619

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

550.77

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.860

Distribution Coefficient, logD

5.860

Water Solubility, LogSw

-5.45

Polar Surface Area

43.046

Acid Dissociation Constant (pKa)

26.31

Base Dissociation Constant (pKb)

-9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.70

K286-3630 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3630 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3630?
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What is the minimum amount of K286-3630 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3630
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3630
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3630 available by request