K286-3679 Screening compound: 2-{[3-(2-ethoxyphenyl)-6-(2-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

K286-3679 Screening compound: 2-{[3-(2-ethoxyphenyl)-6-(2-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide
K286-3679 Screening compound: 2-{[3-(2-ethoxyphenyl)-6-(2-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3679
2-{[3-(2-ethoxyphenyl)-6-(2-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3679

Molecular Formula

C26H24N6O3S3 (C26 H24 N6 O3 S3)

Compound Name

2-{[3-(2-ethoxyphenyl)-6-(2-methylphenyl)-7-oxo-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

IUPAC name

2-{[3-(2-ethoxyphenyl)-6-(2-methylphenyl)-7-oxo-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-5-yl]sulfanyl}-N-(5-methyl-1H-pyrazol-3-yl)acetamide

SMILES

CCOc(cccc1)c1N(C(N=C(N(c1c(C)cccc1)C1=O)SCC(Nc2n[nH]c(C)c2)=O)=C1S1)C1=S

InChI

InChI=1S/C26H24N6O3S3/c1-4-35-19-12-8-7-11-18(19)31-23-22(38-26(31)36)24(34)32(17-10-6-5-9-15(17)2)25(28-23)37-14-21(33)27-20-13-16(3)29-30-20/h5-13H,4,14H2,1-3H3,(H2,27,29,30,33)

InChI Key

HGCPRNORWBIJCC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090667

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

564.71

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.631

Distribution Coefficient, logD

4.629

Water Solubility, LogSw

-4.32

Polar Surface Area

79.847

Acid Dissociation Constant (pKa)

9.86

Base Dissociation Constant (pKb)

1.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

K286-3679 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3679 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3679?
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What is the minimum amount of K286-3679 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3679
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3679
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3679 available by request