K286-3857 Screening compound: 3-(2-fluoro-5-methylphenyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

K286-3857 Screening compound: 3-(2-fluoro-5-methylphenyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
K286-3857 Screening compound: 3-(2-fluoro-5-methylphenyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K286-3857
3-(2-fluoro-5-methylphenyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K286-3857

Molecular Formula

C25H17F2N3OS3 (C25 H17 F2 N3 OS3)

Compound Name

3-(2-fluoro-5-methylphenyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(2-fluoro-5-methylphenyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-6-phenyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

Cc(cc1)cc(N(C(N=C(N(c2ccccc2)C2=O)SCc(cccc3)c3F)=C2S2)C2=S)c1F

InChI

InChI=1S/C25H17F2N3OS3/c1-15-11-12-19(27)20(13-15)30-22-21(34-25(30)32)23(31)29(17-8-3-2-4-9-17)24(28-22)33-14-16-7-5-6-10-18(16)26/h2-13H,14H2,1H3

InChI Key

UZNHMOFMKFCLCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15090774

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.344

Distribution Coefficient, logD

6.344

Water Solubility, LogSw

-5.51

Polar Surface Area

26.654

Acid Dissociation Constant (pKa)

28.33

Base Dissociation Constant (pKb)

0.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

K286-3857 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K286-3857 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K286-3857?
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What is the minimum amount of K286-3857 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K286-3857
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K286-3857
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K286-3857 available by request